The theory treats accurate scattering of electromagnetic radiation by spherical particles of arbitrary size usually comparable to the wavelength of light. In our work, this theory was used to generate the scattering signatures of the Coronavirus. One of the most popular and widely used theories of light scattering is the Mie theory expended for spherical particles. There are various theoretical approaches used for investigating scattered light. The morphological characterization can be carried out either by theoretical or by experimental methods involving light scattering. The incident light used for such investigations is usually laser light of a chosen wavelength which depends upon the type of scattering particles under exploration. This intensity is the source of vital information about the morphology of the scattering particles. The SLS makes use of collecting the intensity of scattered light as a function of the angular distribution. In this work, we have carried out investigations using the SLS approach. īoth the techniques of static light scattering (SLS) and dynamic light scattering (DLS) are proven for their versatility in different areas. Since it is a non-destructive and non-invasive technique, it has been proven to be a significant tool, especially for the investigation and characterization of biological cells. This technique has been widely used in diverse areas like astrophysical applications, biomedical applications, nanoscience applications, application in marine issues, atmospheric applications, and astrobiological applications. ![]() This makes the light scattering technique an interesting approach to exploring small particles ranging from nanometers to micrometer range, to predict their morphology without affecting the particles. In other words, it may provide information about the morphology of the unknown scattering particles under investigation. This diagnostic tool can provide information about various parameters like the shape, size, shape distribution, size distribution, refractive index, density, and composition of the scatterers. The particles may be biological cells, nanoparticles, aerosols, atmospheric dust particles, etc. Light scattering is an important diagnostic tool for particles of different origins. The reports mostly mention the information on the virion structure only, that is, whether it is spherical, elongated, or any other shape. Thus, it becomes important to include the number of spike proteins for any investigation carried out by light scattering technique. It indicates that the number of protein spikes is proportional to the magnitude of pathogenic spread. It thus indicates that the increase in the number of spike proteins per virion increases the possibility of binding into host cells and thereby enhancing the chances of infection. It has been reported by many researchers that the coronavirus enters host cells with the help of these spikes. One important feature of these viruses is the presence of protein spikes on their surface. The investigations on various properties of coronaviruses, primarily by light scattering, may provide novel tools for their identification and analyses. Coronaviruses are a group of RNA viruses that cause a hazard to human health leading to global health issues, thereby affecting economic stability. The concerns caused by these viruses were not taken seriously until their outbreak due to their pathogenic spread and the declaration of a global pandemic. These viruses cause mild to severe respiratory diseases. The novel coronavirus ( SARS-CoV-2) recently classified as a pandemic by the WHO, has threatened the human population worldwide.
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